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It not only protect and beautify the human body functions, will be a variety of harmful volatile substances on human skin have a greater stimulating effect, and some will cause skin edema, itching, rash and other "cosmetic dermatitis." MAC Cosmetics with a high degree of creativity and avant-garde ideas, develop a MAC Cosmetics Outlet unparalleled style. MAC colors bold and innovative, to overturn the traditional style, which uphold, however, are some of the most mundane idea of the spirit, humanity, equality, justice and responsibility of business. Cosmetics and more common life by a variety of colors, flavors, and preservatives, fungicides and other raw materials processing, some special-purpose education are also added hair cosmetics, hair color, perm, breast massage, deodorant, cured spots and sunscreen and other ingredients. Some people use, often appear red and swollen cheek, running water, itching, dermatitis and other skin damage caused by allergy or face, especially the prolonged use of hair dye, is not only easy to cause contact dermatitis, can also cause other diseases. To the number of hair dyes in cosmetics cause allergic reactions side effects of most of the. According to the survey, a large number of blood diseases and the use of hair dye susceptible to Hodgkin disease. Therefore, cosmetics should not underestimate the side effects. On the one hand to minimize the use, not abuse; the other hand, carefully selected, be sure to use good quality, side effects, the characteristics of cosmetics for your skin. Of itself has a history of skin allergies, especially to be careful, if you have white skin, cosmetics, once found to have adverse reactions should be immediately discontinued. There is also a source of side-effects is deterioration due to improper use. Usually the most important component of cosmetic oil and water, the breeding of micro-organisms also need water, so as long as containing water, will result in cosmetic products of bacterial contamination, spoilage, others such as glycerol, polyols and other moisturizing ingredients can provide bacteria microorganisms such as carbon source of protein, amino acids and other major components of nitrogen provides the best source of microorganisms in the use of cosmetics during the product switch and the opportunity to direct contact with the fingers may be nearly a hundred times or more, very easy to speed up the bacteria and other microbial infections, if not properly added the so-called preservatives or antimicrobial agents, it is easy to cause oxidation or contamination of cosmetic deterioration. MAC Cosmetics is seen in the history of the world's most innovative cosmetics, one of the most influential brands. This was established in 1984, professional make-up brand, always adhere to high standards and creative development needs. Today, MAC Cosmetics has standing to lead the fashion, beauty and pop culture, cutting-edge position. MAC Cosmetics in the creation of new products and outstanding ability to develop new markets. mac makeup stockists Uses Specific zones of abnormally high pigmentation such as moles and birthmarks may be depigmented to match to the surrounding skin. Conversely, in cases of vitiligo, unaffected skin may be lightened to achieve a more uniform appearance. However, in cases where these spot treatment creams are used in attempt to lighten the entire complexion, all of the current methods are considered ineffective. Complete skin depigmentation is simply a futile process. An additional application is genital or anal bleaching, intended to reduce the typically darker pigmentation of the genital and perianal area. History In Japan, geisha were (and still are) known for their painted white skin, which represents beauty, grace, and high social status. However, the skin-whitening products are not used in such a wide scale in Japan today. Geisha paint their skin white in geisha-based ceremonies to celebrate their culture and background. Today, skin whitening products are available in the form of creams, pills, soaps or lotions. The mechanism of permanent whitening is usually by the breakdown of melanin by enzymes, such as that contained in the droppings of the Japanese bush warbler or reducing agents such as hydroquinone. Most whitening creams also contain a UV block to prevent sun damage to the skin. Skin whitening creams (fairness creams) are used extensively in India and among the Indian diaspora abroad. In India, these creams are marketed towards all groups from rural villagers to urban professionals. The creams are also sold throughout the rest of Asia, Africa, Latin America and the Middle East. The whitening cream industry is estimated to be worth around $432 million in India and $7 billion in China. Due to the increasing trend of targeting male consumers and endorsements by celebrities such as Indian actor Shahrukh Khan, sales have increased at a rate of 14% in non-European markets in only the last year. Further information: History of cosmetics Melanin and pigmentation Uneven pigmentation affects most people, regardless of ethnic background or skin color. Skin may either appear lighter or darker than normal; there may be blotchy, uneven areas, patches of brown to gray discoloration or freckling. Skin pigmentation disorders occur because the body produces either too much or too little melanin. Melanin is the pigment produced by melanocyte cells. It is triggered by an enzyme called tyrosinase, which creates the color of skin, eyes, and hair shades. Melanin has two major forms that combine to create varying skin tones. Eumelanin produces a range of brown skin and hair color, while pheomelanin imparts a yellow to reddish hue. Melanin provides some amount of sun protection for the skin by absorbing ultraviolet light. Darker skin colors are less susceptible to sunburn and the overall effects of sun damage. Increased melanin production also known as hyperpigmentation is often referred to as melasma, chloasma or solar lentigenes. Melasma is a general term describing darkening of the skin. Chloasma is generally used to describe skin discolorations caused by hormones. These hormonal changes are usually the result of pregnancy, birth control pills or estrogen replacement therapy. Solar lentigenes is the technical term for darkened spots on the skin caused by the sun. Solar refers to sunlight and lentigene describes a darkened area of skin. These spots are quite common in adults with a long history of unprotected sun exposure. Aside from sun exposure and hormones, hyperpigmentation can be caused by skin damage, such as remnants of blemishes, wounds or rashes. This is especially true for those with darker skin tones. The most typical cause of darkened areas of skin, brown spots or areas of discoloration is unprotected sun exposure. Once incorrectly referred to as liver spots, these pigment problems are not connected with the liver. On lighter to medium skin tones, solar lentigenes emerge as small- to medium-sized brown patches of freckling that can grow and accumulate over time on areas of the body that receive the most unprotected sun exposure, such as the back of the hands, forearms, chest, and face. For those with darker skin colors, these discolorations can appear as patches or areas of ashen-gray skin. Combination treatments Most skin-lightening treatments, which can reduce or block some amount of melanin production, are aimed at inhibiting tyrosinase. Many treatments use a combination of topical lotions or gels containing melanin-inhibiting ingredients along with a sunscreen, and a prescription retinoid. Depending on how the skin responds to these treatments, exfoliants either in the form of topical cosmetic or chemical peels and lasers may be used. New development using LED systems are showing good results also Topical treatments Topical hydroquinone is considered by many dermatologists to be a safer, similarly effective (if not more so), and less expensive option than lasers or deep peel treatments. Topical hydroquinone comes in 2% (available in cosmetics) to 4% (or more) concentrations (available from a physician or by prescription), alone or in combination with tretinoin 0.05% to 0.1%. Research has shown hydroquinone and tretinoin to be powerful tools against sun- or hormone-induced melasma. Hydroquinone has been shown to cause leukemia in mice and other animals. The European Union banned it from cosmetics in 2001, but it shows up in bootleg creams in the developing world. It is sold in the United States as an over-the-counter drug, but with a concentration of hydroquinone not exceeding 2 percent. Some research has shown topical azelaic acid in 15% to 20% concentrations to be as efficacious as hydroquinone with a decreased risk of irritation. Tretinoin by itself has also been shown to be useful in treating hyperpigmentation of sun-damaged skin. Kojic acid, alone or in combination with glycolic acid or hydroquinone, also has shown good results due to its inhibitory action on tyrosinase (though kojic acid has had problems in terms of stability and potential negative effects on the skin and is rarely used today). Several plant extracts and vitamin C also have some research showing them to be effective for inhibiting melanin production. Niacinamide is claimed to be a much safer alternative when applied topically for skin or genitalia whitening.[citation needed] According to a cosmetic company, it has no adverse side-effects and as well as acne reduction, also increases skin moisture and reduces fine wrinkles. Mercury Many skin whiteners contain toxic mercury such as mercury(II) chloride or ammoniated mercury as the active ingredient. Hydroquinone In medical literature, hydroquinone is considered the primary topical ingredient for inhibiting melanin production. Its components have potent antioxidant abilities. Hydroquinone is a strong inhibitor of melanin production, meaning that it prevents skin from making the substance responsible for skin color. Hydroquinone does not bleach the skin but lighten, and can only disrupt the synthesis and production of melanin hyperpigmentation. It has been banned in some countries (e.g. France) because of fears of a cancer risk. Some concerns about hydroquinone's safety on skin have been expressed, but the research when it comes to topical application indicates negative reactions are minor or a result of using extremely high concentrations or from other skin-lightening agents such as glucocorticoids or mercury iodine. This is particularly true in Africa where adulterated skin lightening products are commonplace. Because of hydroquinone's action on the skin, it can be irritant, particularly in higher concentrations of 4% or greater and predictably when combined with tretinoin. Some medications have been created that combine 4% hydroquinone with tretinoin and a form of cortisone. The cortisone is included as an anti-inflammatory. The negative side effect of repeated application of cortisone is countered by the positive effect of the tretinoin so that it does not cause thinning of skin and damage to collagen. Hydroquinone can be an unstable ingredient in cosmetic formulations. When exposed to air or sunlight it can turn a strange shade of brown. Therefore, when you are considering a hydroquinone product, it must be packaged in a non-transparent container that minimizes light and air exposure. Hydroquinone products packaged in jars are not recommended because they become ineffective shortly after opening. Alternatives to hydroquinone Some of alternative lighteners are derivatives of hydroquinone. They include Mitracarpus scaber extract, Uva ursi (bearberry) extract, Morus bombycis (mulberry), Morus alba (white mulberry), and Broussonetia papyrifera (paper mulberry). All of these contain arbutin (technically known as hydroquinone-beta-D-glucoside), which can inhibit melanin production. Pure forms of arbutin are considered more potent for affecting skin lightening (alpha-arbutin, beta-arbutin, and deoxy-arbutin). Other options with some amount of research regarding their potential skin lightening abilities are licorice extract (specifically glabridin), azelaic acid, and stabilized vitamin C (L-ascorbic acid, ascorbic acid, and magnesium ascorbyl phosphate). There is also a small amount of research showing oral supplements of pomegranate extract, ellagic acid, vitamin E, and ferulic acid can inhibit melanin production. Arbutin Arbutin is derived from the leaves of bearberry, cranberry, mulberry or blueberry shrubs, and also is present in most types of pears. It can have melanin-inhibiting properties. Concentration protocols have yet to be established for arbutin, meaning it is not known how much arbutin it takes to lighten skin when it is added to a cosmetic formulation. Moreover, there are patents controlling its use for skin lightening. Many cosmetics companies use plant extracts that contain arbutin. There is little to no research showing the plant extract source of arbutin as having any impact on skin, especially not in the tiny amounts used in cosmetics.[citation needed] Tretinoin Research has shown that the use of tretinoin (also known as all-trans retinoic acid) can only be somewhat effective in treating skin discolorations. Alpha hydroxy acids Alpha hydroxy acids (AHAs) primarily in the form of lactic acid and glycolic acid are the most researched forms of AHAs because they have a molecular size that allows effective penetration into the top layers of skin. It is generally assumed that in and of themselves AHAs in concentrations of 4% to 15% are not effective for inhibiting melanin production and will not lighten skin discolorations in that manner. It is believed that their benefit is in helping cell turnover rates and removing unhealthy or abnormal layers of superficial skin cells (exfoliation) where hyperpigmented cells can accumulate. However, other research has shown that lactic and glycolic acids can indeed inhibit melanin production separate from their actions as an exfoliant on skin. Like laser treatments, alpha hydroxy acid peels (using 50% concentrations or greater) may remove skin discolorations. Only a qualified physician should perform these types of facial peels. Kojic acid Kojic acid is a by-product in the fermentation process of malting rice for use in the manufacturing of sake, the Japanese rice wine. Some research shows kojic acid to be effective for inhibiting melanin production. However, kojic acid is an unstable ingredient in cosmetic formulations. Upon exposure to air or sunlight it can turn brown and lose its efficacy. Many cosmetic companies use kojic dipalmitate as an alternative because it is more stable in formulations. However, there is no research showing kojic dipalmitate to be as effective as kojic acid, although is it a good antioxidant. Further, some controversial research has suggested that kojic acid may have carcinogenic properties in large doses. Azelaic acid Azelaic acid is a component of grains, such as wheat, rye, and barley. It is applied topically in a cream formulation at a 20% concentration. Azelaic acid is used to treat acne, but there also is research showing it to be effective for skin discolorations. Other research also indicates azelaic acid may be an option for inhibiting melanin production. Vitamin C Magnesium ascorbyl phosphate, L-ascorbic acid, ascorbyl glucosamine, and ascorbic acid are various forms of vitamin C considered stable and effective antioxidants for skin.[citation needed] There are very few studies showing them to have benefit for inhibiting melanin production. The concentrations of these ingredients used in tests were generally high (more than 5%), which is rarely used in cosmetic formulations.. Glutathione Glutathione is one of the components of amino acids. It is mostly an antioxidant like vitamin C. Skin whitening is a side effect of this. But it becomes effective in glutathione if a person takes 2 - 4 tablets of glutathione after taking 1,000 - 2,000 mg of tablets of vitamin C which was taken after a meal. This is where skin whitening becomes also effective in vitamin C. Laser treatments Both ablative and nonablative lasers can have a profound effect on melasma. However, the results are not always consistent, and problems have been reported (such as hypo- or hyperpigmentation). Laser treatments of this kind are more likely to result in problems for those with darker skin tones. Cryosurgery Another alternative to laser treatment is cryosurgery using liquid nitrogen. Controlled destruction of skin cells causes the skin to naturally regenerate itself. Excess melanin comes to the surface and peels off in a few days. This is particularly useful in sensitive areas like the genitals where laser treatment could leave a scar. Efficacy of the treatment depends on the depth of the pigment. Freckles in any part of the body can be treated the same way.[citation needed] Fruits Many fruits have skin whitening effect when they are eaten or scrubbed on skin. The leading fruit is papaya, wherein its enzyme papain can lighten the skin. Other notable fruits are lemon, lime, calamondin, and orange; all of these have Vitamin C which is said to have a skin whitening effect.[citation needed] See also Venetian Ceruse - white lead based cosmetic worn by Elizabeth I of England. Sun tanning Colonial mentality Hydroquinone Facial Pale (skin tone) Tooth bleaching Whiteness in Japanese culture References ^ Ntambwe, Malangu, Why is skin lightening practiced?, Science in Africa magazine, National School of Public Health at the Medical University of South Africa, March 2004 ^ India's hue and cry over paler skin, Daily Telegraph, 1 Jul 2007 ^ Counter, S. Allen, Whitening skin can be deadly, Boston Globe, 16 Dec 2003 ^ Rashid, Aliya, A rush to cream the fairness fetish, Dai ^ Shades of Difference: Why Skin Color Matters. Stanford University Press. 2009. pp.177188. ISBN 0804759995. ^ Saikat Chatterjee (November 12, 2009). "Fair-Skin Fashion Boosts Sales of Whitening Creams in India". Bloomberg. . Retrieved 2009-12-10. ^ Cutis, August 2005, pp 19-23 ^ Journal of the American Academy of Dermatology, May 2006, supplemental, pages 272-281; Dermatologic Surgery, March 2006, pages 365-371; Journal of Drugs in Dermatology, September-October 2004, supplemental, 27-34; International Journal of Dermatology, December 2003, pages 966-972; and Archives of Dermatology, December 2002, pages 1578-1582). ^ Dermatologic Surgery, March 2006, pages 365-371. ^ A Vision of Pale Beauty Carries Risks for Asia's Women - New York Times ^ Journal of the American Academy of Dermatology, May 2006, pages S272-S281; International Journal of Dermatology, August 2004, pages 604-607; and The American Journal of Clinical Dermatology, September-October 2000, pages 261-268). ^ Procter & Gamble. "Skin lightening products" (PDF). . ^ "Skin lightening products". . ^ Cutis, March 2006, pages 177-184; Journal of Drugs in Dermatology, September-October 2005, pages 592-597; Journal of Cosmetic Science, May-June 1998, pages 208-290; Dermatological Surgery, May 1996, pages 443-447. ^ Journal of Natural Products, November 2002, pages 1 605-1611. ^ Journal of Dermatological Science, August, 2001, supplemental, pages 68-75. ^ British Journal of Dermatology, March 2003, pages 493-500 and Critical Reviews in Toxicology, May 1999, pages 283-330. ^ Drugs in Dermatology, July-August 2004, pages 377-381. ^ Experimental Dermatology, August 2005, pages 601-608; Bioscience, Biotechnology, and Biochemistry, December 2005, pages 2368-2373; International Journal of Dermatology, August 2004, pages 604-607; Journal of Drugs in Dermatology, July-August 2004, pages 377-381; acial and Plastic Surgery, February 2004, pages 3-9; Dermatologic Surgery, March 2004, pages 385-388; Journal of Bioscience and Bioengineering, March 2005, pages 272-276; Journal of Biological Chemistry, November 7, 2003, pages 44320-44325; Journal of Agriculture and Food Chemistry, February 2003, pages 1201-1207; International Journal of Cosmetic Science, August 2000, pages 291-303; and Anti-Cancer Research, September-October 1999, pages 3769-3774). ^ The Journal of Pharmacology and Experimental Therapeutics, February 1996, pages 765-769. ^ Dermatologic Surgery, March 2006, pages 365-371; Acta Dermato-Venereologica, July 1999, pages 305-310; International Journal of Dermatology, April 1998, pages 286-292; and Journal of the American Academy of Dermatology, March 1997, pages S27-S36. ^ Experimental Dermatology, January 2003, supplemental. pages 43-50. ^ Dermatologic Surgery, February 2005, pages 149-154; Journal of Cutaneous Medicine and Surgery, April 2004, pages 97-102; Cutis, February 2004, supplemental, pages 18-24; Dermatologic Therapy, June 2004, pages 196-205; and Dermatological Surgery, June 1999, pages 450-454. ^ Archives of Pharmacal Research, August 2001, pages 307-311. ^ Mutation Research, Genetic Toxicology and Environmental Mutagenesis, June 2005, pages 133-1450 and Toxicological Sciences, September 2004, pages 43-49. ^ International Journal of Dermatology, December 1991, pages 893-895. ^ Journal of the American Academy of Dermatology, May 2006, supplemental, pages 272-281. ^ International Journal of Dermatology, August 2004, page 604; Dermatology, April 2003, pages 316-320; Journal of the American Academy of Dermatology, January 1996, pages 29-33; ^ Journal of the American Academy of Dermatology, May 2006, supplemental, pages 262-271; Dermatologic Therapy, January 2001, page 46; Journal of Cosmetic and Laser Therapy, March 2005, pages 39-43; Journal of Cutaneous Medicine and Surgery, April 2004, pages 97-102; Journal of Drugs in Dermatology, November-December 2005, pages 770-774; Dermatologic Surgery, October 2005, page 1263; and Lasers in Surgery and Medicine, April 2000, pages 376-379. 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